Wine News: Red Wine Rivals Diabetes Drug in Lab Tests
May 18, 2011
Researchers working in biotechnology laboratories in Vienna have found that red wine contains favorable levels of a chemical found in drugs used treat type 2 diabetes patients. In time, they say, red wine treatments may offer an supplemental approach to current therapies.
The results of their research were published in the January issue of Food & Function. The team tested the chemical composition of two white wines from Austria and 10 reds. In the most promising experiment, 100 milliliters of a 2003 Blaufränkisch contained four times the ligands found in the the recommended daily dose of rosiglitazone, a commercially available drug used to treat type 2 diabetes, manufactured by GlaxoSmithKline and marketed as Avandia. Ligands are sticky molecules associated with preventing blood clots, reducing inflammation and optimizing cholesterol digestion.
Type 2 diabetes is a metabolic disease characterized by the body’s inability to use insulin to regulate blood-sugar levels. Clinical studies on animals show that red wine may help protect against developing the disease. “However, the molecular modes of action and the different pathways involved are not yet fully understood for most of the active compounds present in red wines,” wrote lead researcher Alois Jungbauer, a biotechnologist at Vienna’s University of Natural Resources and Life Sciences.
Ligands contain polyunsaturated fatty acids that bind to cholesterol in the body’s tissues and transport it to the liver for excretion. The inability to get rid of cholesterol is a precursor to metabolic syndrome. “Metabolic syndrome is correlated with reduced insulin sensitivity, hypertension and hence a higher risk for development of type 2 diabetes and cardiovascular disease,” wrote the authors. Regular doses of ligands could prevent metabolic syndrome and reduce the chances of type 2 diabetes.
Food & Function deputy editor Kathleen Too wrote in an accompanying editorial that the findings may provide a basis for a one-two punch against the risk of metabolic syndrome. “They found that not only did these compounds bind to [cholesterol], but that the wine contained enough of them to rival the activity of the potent drug rosiglitazone.”
Not all wines are created equal in this regard, however. The aforementioned Blaufrankisch contained high levels of the chemicals, with 1.71 grams per liter. Second was a 2004 Zweigelt with 1.65 grams per liter. A 2005 Zweigelt contained less, which leads Jungbauer to conclude that different environmental conditions across vintages, as well as differing winemaking techniques, may greatly change the chemical profile of wine.
Nonetheless, none of the 10 reds contained less than 1 gram per liter of measurable polyphenols. The white wines, which are not exposed to grape skins for a prolonged period of time, contained below 0.10 grams per liter.
Chi-Tang Ho, a food researcher at Rutgers School of Environmental and Biological Sciences told Too that the results provide evidence to support moderate red wine consumption, but that the impact of alcohol on the body needs consideration. Those who wish to avoid alcohol may look to other sources rich in similar polyphenols, such as tea and certain fruits.
While red wine cannot be considered an alternative treatment to any of the above ailments, Jungbauer did not discount the power of alternative therapies in the future. “Grape skin extracts have great potential, and although the influence of ethanol is not yet fully understood, I am confident that it will be possible to replace some synthetic compounds by plant extracts,” said Jungbauer.
Best restaurant in Clark Philippines offers award winning restaurant wine list, top rated fine dining resto bar outside Manila.
Where to eat in Clark Pampanga, good restaurants where children and kids can go? Listings of the finest and most frequently visited restaurants in Pampanga, Angeles City, Subic and Clark Freeport show that although Yats Restaurant is a world class fine dining resto bar, this top rated restaurant located inside Mimosa Golf Estate near the golf course and casino of Clark is a popular place to eat and dine out for families with kids. This popular restaurant in Clark is very child friendly and is also generally regarded as the best restaurant in Pampanga, Angeles city, Subic and Clark Philippines.
Manila residents and tourists look for a good restaurant in Clark to wine and dine, relax and unwind after a game of golf or a long day of work or business in Pampanga. Top rated and most frequently visited restaurant in Clark is Yats Restaurant and Wine Lounge. Even families with children choose to eat at this restaurant because of its child friendly facilities, good service and excellent food.
Best restaurant in Clark Philippines offers award winning restaurant wine list, top rated fine dining resto bar outside Manila, one in 650 restaurants in the world to win the Wine Spectator’s Best of Awards of Excellence for its fabulous restaurant wine list, the only restaurant in the Philippines to be given this award.
Each year, world leading wine and dining magazine called Wine Spectator gives out a special award to restaurants offering the best wine selections. The Best of Awards of Excellence is given out to less than 700 of the best restaurants worldwide. Here in the Philippines, Yats Restaurant and Wine Bar is the only one to receive this prestigious international award. Restaurant wine lists are judged not for the number of impressive bad names on the wine list but more on how interesting the wine selection is for the dining guests. Breadth of selection covering all the major wine producing regions of the world is an important aspect of a restaurant wine list and so is the depth of vintages offered. Yats Restaurant has long been recognized internationally as one of the best places to wine and dine for wine lovers and those who are used to world class gourmet dining. Winning this international restaurant award places the Philippines on the map of international travelers who are accustomed to fine dining at a world-class level. The famous restaurant wine list of this top rated restaurant in Clark Pampanga serves as an icon in the Philippines for international wine lovers coming over to visit the Philippines on business or leisure.
For comments, inquiries and reservations click on Click here for inquiry and reservations
Restaurant@Yats-International.com
(045) 599-5600
0922-870-5178
0917-520-4401
Ask for Pedro and Rechel
Getting to this fine dining restaurant of Angeles City Clark Freeport Zone Pampanga Philippines
How to get to this fine-dining restaurant in Clark Pampanga? Once you get to Clark Freeport, go straight until you hit Mimosa. After you enter Mimosa, stay on the left on Mimosa Drive, go past the Holiday Inn and Yats Restaurant (green top, independent 1-storey structure) is on your left. Just past the Yats Restaurant is the London Pub.
Yats Restaurant & Wine Bar
Mimosa Drive past Holiday Inn, Mimosa Leisure Estate,
Clark Freeport Zone, Pampanga, Philippines 2023
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Exchange Rd Ortigas Metro Manila, Philippines 1605
(632) 637-5019 0917-520-4393 Rea or Chay
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