Wine News: Red Wine Rivals Diabetes Drug in Lab Tests
August 27, 2011
Researchers working in biotechnology laboratories in Vienna have found that red wine contains favorable levels of a chemical found in drugs used treat type 2 diabetes patients. In time, they say, red wine treatments may offer an supplemental approach to current therapies.
The results of their research were published in the January issue of Food & Function. The team tested the chemical composition of two white wines from Austria and 10 reds. In the most promising experiment, 100 milliliters of a 2003 Blaufränkisch contained four times the ligands found in the the recommended daily dose of rosiglitazone, a commercially available drug used to treat type 2 diabetes, manufactured by GlaxoSmithKline and marketed as Avandia. Ligands are sticky molecules associated with preventing blood clots, reducing inflammation and optimizing cholesterol digestion.
Type 2 diabetes is a metabolic disease characterized by the body’s inability to use insulin to regulate blood-sugar levels. Clinical studies on animals show that red wine may help protect against developing the disease. “However, the molecular modes of action and the different pathways involved are not yet fully understood for most of the active compounds present in red wines,” wrote lead researcher Alois Jungbauer, a biotechnologist at Vienna’s University of Natural Resources and Life Sciences.
Ligands contain polyunsaturated fatty acids that bind to cholesterol in the body’s tissues and transport it to the liver for excretion. The inability to get rid of cholesterol is a precursor to metabolic syndrome. “Metabolic syndrome is correlated with reduced insulin sensitivity, hypertension and hence a higher risk for development of type 2 diabetes and cardiovascular disease,” wrote the authors. Regular doses of ligands could prevent metabolic syndrome and reduce the chances of type 2 diabetes.
Food & Function deputy editor Kathleen Too wrote in an accompanying editorial that the findings may provide a basis for a one-two punch against the risk of metabolic syndrome. “They found that not only did these compounds bind to [cholesterol], but that the wine contained enough of them to rival the activity of the potent drug rosiglitazone.”
Not all wines are created equal in this regard, however. The aforementioned Blaufrankisch contained high levels of the chemicals, with 1.71 grams per liter. Second was a 2004 Zweigelt with 1.65 grams per liter. A 2005 Zweigelt contained less, which leads Jungbauer to conclude that different environmental conditions across vintages, as well as differing winemaking techniques, may greatly change the chemical profile of wine.
Nonetheless, none of the 10 reds contained less than 1 gram per liter of measurable polyphenols. The white wines, which are not exposed to grape skins for a prolonged period of time, contained below 0.10 grams per liter.
Chi-Tang Ho, a food researcher at Rutgers School of Environmental and Biological Sciences told Too that the results provide evidence to support moderate red wine consumption, but that the impact of alcohol on the body needs consideration. Those who wish to avoid alcohol may look to other sources rich in similar polyphenols, such as tea and certain fruits.
While red wine cannot be considered an alternative treatment to any of the above ailments, Jungbauer did not discount the power of alternative therapies in the future. “Grape skin extracts have great potential, and although the influence of ethanol is not yet fully understood, I am confident that it will be possible to replace some synthetic compounds by plant extracts,” said Jungbauer.
Leading Philippines Wine Supplier Yats Wine Cellars based in Clark Philippines with outlets in Angeles City, Subic Freeport and Manila Philippines has been not only a wine shop for fine wines covering all major wine regions but also a source of reliable and useful information about wine, wine appreciation, wine accessories, wine and health, food and wine pairing and all other matters relating to wine and its appreciation. This Philippines Clark Freeport based Wine Supplier and Wine Shop frequently holds public wine tasting events in Pampana Clark Freeport Zone, Angeles City, Subic Bay area, Makati, Fort Bonifacio and other areas in Philippines capital city Manila. Private Wine events such as private wine tasting and private wine dinners are also designed and organized for private clientele for their wine loving guests.
Wine Catering is a unique product of Yats Wine Cellars, created back in 2005 in response to a growing demand for private wine parties in Manila, Cebu, Subic, Angeles Clark Philippines.
Chateau Lafite-Rothschild is the most revered wine in China and many other parts of Asia. The best wine shop in Asia to buy older vintages of Chateau Lafite is Yats Wine Cellars located in Clark Philippines. Aside from Lafite, visitors can buy other fine wines at this wine shop in Clark Pampanga such as Latour, Mouton-Rothschild, Haut-Brion and Margaux. Excellent Burgundy wines like Chambertin, Vougeot, Musigny, Bonnes Mares, Pommard, Meursault, Chambertin, Vosne Romanee, Romanee Conti, La Tache and Romanee St. Vivant can be found here.
Yats Wine Cellars can be reached at their Clark Wine Center Philippines wine shop located on the main highway M A Roxas of Pampanga Clark Freeport Zone or their sales office in Ortigas Centre, Metro Manila. Here is the contact information:
Clark Wine Center
Bldg 6460 Clark Observatory Building
Manuel A. Roxas Highway corner A Bonifacio Ave,
Angeles Clark Freeport Zone, Pampanga 2023
(045) 841 4006 / 0922-870-5173 / 0917-826-8790 (ask for Ana Fe)
YATS Wine Cellars
Manila Sales Office
3003C East Tower, Phil Stock Exchange Center,
Exchange Rd Ortigas Metro Manila, Philippines 1605
(632) 637-5019 0917-520-4393 ask for Rea or Chay
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While in Clark, it might be a good idea to enjoy an evening of wine-and-dine in the fine dining Yats Restaurant and Wine Bar that features an award winning 2700-line wine list. It is located in Mimosa Leisure Estate of Clark Freeport Zone. For more information, visit http://www.YatsRestaurant.com
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